Q: If Nova’s ability defeats an attacking enemy, does that enemy’s attack still deal damage?

A: No. Although the attack sequence has initiated, damage from that attack has not yet been calculated. If Nova defeats the enemy during this step, the rest of the attack sequence fails to resolve. -(Official FAQ)

If you can build for a steady drip of - which is easier than ever thanks to Enhanced Reflexes - Nova can put out an impressive amount of damage.

Captain Marvel and Iron Man are likely to have the biggest incentive to stack energy right now.